FAQ for Clinicians
Have questions about PolypDx™? We have compiled a list of frequently asked questions.
Test results are reported qualitatively as a positive or negative.
For Positive PolypDx™ results:
There is a strong likelihood of adenomatous polyps being present.
For Negative PolypDx™ results:
There is a lower likelihood of adenomatous polyps being present.
The benefits of PolypDx™ are:
Early stage detection: PolypDx™ detects adenomatous polyps, the precursor to colorectal cancer, thereby detecting individuals at risk for colorectal cancer.
High patient compliance: PolypDx™ does not require any unpleasant bowel cleansing preparation, nor unsanitary handling of stool or blood collections.
Ease of use:
PolypDx™ is fast and simple to collect – just a small urine sample is required with no dietary or medication restrictions.
PolypDx™ has a high sensitivity for colonic adenomatous polyp detection. PolypDx™ was validated in a clinical trial of 876 patients, demonstrating a high sensitivity for detecting adenomatous polyps.
Cost-effective and high-throughput platform:
PolypDx™ is a mass-spectrometer-based laboratory test, therefore allowing high-throughput and cost-effective population-based screening.
The risks of PolypDx™ are:
There are no known direct risks to the patient since only a urine sample is needed. However, as with any laboratory test there is the possibility of a false-negative or false-positive test result.
PolypDx™ is currently available in the United States as a laboratory developed test through a Clinical Laboratory Improvement Amendments (CLIA) certified laboratory. If you are a US resident and require more information, please see getpolypdx.com.
Results will be sent back within two weeks of the laboratory receiving the sample.
PolypDx™ is a non-invasive test designed to measure small molecules (metabolites) in urine that are associated with the presence of adenomatous polyps in the colon and rectum. The concentrations of the metabolomics markers are quantified and analyzed using a validated algorithm to determine the likelihood of a polyp being present.
Metabolomics is a new “omics” science which characterizes low molecular weight compounds generated by metabolism. There are over 40,000 known metabolites in the human body and their specific concentrations provide a snapshot of an individual’s current health state.
PolypDx™ is currently available as a self-pay test.
More information on the test is available at firstname.lastname@example.org.